7 Colonial Way, Watford WD24 4JU, Great Britain
+44 753 718 0907
Mifepristone Abortion Pill Online

Buy Mifepristone Online

Before deciding on your treatment, be sure to consult a specialist!

Mifepristone Abortion Pill — commonly known as the Mifepristone pill. The Mifepristone pill is a significant drug in the Medical Abortion procedure (with Misoprostol) and is available in generic form (order Abortion Kit, which contains both medicines). It is an entirely risk-free procedure of abortion.

The United States legalized abortion almost twenty years ago. Millions of women have taken Mifepristone since then to terminate pregnancies safely. Clinical trials showed a 98 percent success rate when used in combination with Misoprostol. So, if you want to buy Mifepristone, you have found the best place to do it. Mifepristone may be used for an abortion if the pregnancy lasts fewer than 11 weeks.

Specifications

  • Usage: Component of Abortion Pills (MTP)
  • Active Ingredients: Mifepristone 25 mg
  • Supplied Form: Tablets
  • Packaging: Blister pack with 10 pills
  • Production: India

In Stock

Shipping Info

All of our parcels pass through customs without difficulty!

  • Express Shipping:
    USA - $100 (1-2 working days)
    EU - $100 (3-7 working days)
  • Standard Shipping: (5-7 working days)
    US, Canada, Asia – $50
150$
190$

Product description

Active substance:

Mifepristone

ATC Codes:

G03XB01 — Mifepristone

Pharmacological Group:

Abortive (antigestagenic) drugs.

Mechanism of Action of Mifepristone

This steroid drug has a modest androgenic effect and inhibits progestogenic receptors, resulting in decreased progesterone synthesis. Mifepristone’s anti-progestational effects stem from its competitive interaction with progesterone at progesterone-receptor sites. Studies in various animal species indicate that the compound inhibits the activity of endogenous or exogenous progesterone, leading to pregnancy termination. In the treatment of Cushing’s syndrome, mifepristone blocks cortisol binding to its receptor, mitigating the effects of excess cortisol without reducing cortisol production.

The medication also boosts the muscle layer’s sensitivity to prostaglandins, promotes the production and release of a potent anti-inflammatory cytokine (interleukin 8), and raises the contractility of the uterus’s middle layer (the myometrium).

When embryo implantation is rejected, and the embryo is evacuated, the uterine mucous membrane changes. The chemical also inhibits ovulation, changes the endometrium, and hinders zygote implantation.

Pharmacodynamics:

Mifepristone, a synthetic steroid with anti-progestational effects, is used for medically terminating intrauterine pregnancies up to 49 days. Doses of 1 mg/kg or higher antagonize progesterone’s effects on the endometrium and myometrium in women. During pregnancy, it sensitizes the myometrium to prostaglandin-induced contractions. Additionally, mifepristone exhibits antiglucocorticoid and weak antiandrogenic properties. In rats, it inhibits the activity of the glucocorticoid dexamethasone at doses between 10 and 25 mg/kg. In humans, doses of 4.5 mg/kg or more lead to an increase in adrenocorticotropic hormone (ACTH) and cortisol levels.

Absorption:

The absolute bioavailability of a 20 mg oral dose is 69%.

Toxicity:

Most women receiving mifepristone experience adverse reactions, with about 90% reporting side effects after taking misoprostol on day three of the treatment. Common reactions include heavy bleeding, abdominal pain, cramping, nausea, vomiting, and diarrhea.

Food Interactions:

Avoid grapefruit products, as grapefruit inhibits mifepristone metabolism through the CYP3A4 pathway, leading to increased serum levels. Taking mifepristone with food has been shown to elevate serum levels.

Pharmacokinetic Properties

Mifepristone is quickly absorbed once 200 mg is administered orally (orally). The medicine reaches its maximal concentration in the blood after an average of 1.3 hours.

The half-life is about 18 hours. Almost all medications are bound to proteins in the blood, namely albumins and glycoproteins. The liver controls mifepristone’s oxidative biotransformation. Most of the medication is excreted via feces, with 10% eliminated through urine.

Buy Mifepristone
Buy Mifepristone

Indications for the Use of Mifepristone:

  1. Medical termination of a physiological pregnancy as early as possible, up to 77 days of amenorrhea (in combination with Misoprostol);
    Inducing labor artificially to facilitate a successful delivery at term;
  2. Preparing the cervix conservatively for a surgical abortion in the first trimester to soften and open it;
  3. In the event of intrauterine fetal mortality, inducing labor artificially when oxytocin and prostaglandin usage is contraindicated;
  4. Leiomyoma is a benign, monoclonal uterus tumor that often doesn’t grow more significant than 12 weeks.

Medical Termination of a Physiological Pregnancy

The process of medical termination with Mifepristone typically involves two steps. The first step is the administration of Mifepristone, usually in the form of a pill taken orally. Mifepristone works to block progesterone receptors, causing the uterine lining to break down and the pregnancy to detach from the uterine wall.

The second step involves the administration of Misoprostol, a prostaglandin medication that causes the uterus to contract and expel the pregnancy. Misoprostol is typically taken 24 to 48 hours after Mifepristone to complete the abortion process.

Benefits of Medical Abortion with Mifepristone:

  1. Non-invasive: Medical termination with mifepristone is a non-invasive procedure that does not require surgery.
  2. Early gestational age: It is most effective in the early stages of pregnancy, typically up to 10 weeks gestation.
  3. Privacy: Medical termination can be done in the privacy of one’s home, avoiding the need for hospital visits.
  4. Lower risk of complications: Compared to surgical abortion, medical termination with mifepristone has a lower risk of complications such as infection or injury to the uterus.

Risks and Considerations of Medical Abortion with Mifepristone:

While medical termination with mifepristone is generally safe and effective, there are some risks and considerations to keep in mind. These may include:

  • Incomplete abortion, requiring additional intervention;
  • Heavy bleeding or hemorrhage;
  • Infection;
  • Allergic reactions to the medication.

It is important for individuals considering medical termination with mifepristone to consult a healthcare provider to discuss their options, risks, and follow-up care.

Cervical Preparation with Mifepristone

Mifepristone is commonly used to prepare the cervix for procedures such as:

  1. Surgical Abortions: Before a surgical abortion, Mifepristone may be administered to soften and dilate the cervix, making the procedure smoother and more comfortable for the patient.
  2. Hysteroscopies: A hysteroscopy is a procedure that allows doctors to view the inside of the uterus. Preparing the cervix with Mifepristone can facilitate the insertion of the hysteroscope.
  3. Intrauterine Device (IUD) Insertions: Mifepristone may be used before an IUD insertion to help dilate the cervix, making the process less painful.

Administration and Dosage of Mifepristone in Cervical Preparation

Mifepristone for cervical preparation is typically administered orally in a healthcare provider’s office or clinic. The dosage and timing of Mifepristone may vary depending on the specific procedure and the individual patient’s medical history. It is essential to follow the healthcare provider’s instructions carefully and to disclose any relevant medical information, including allergies and current medications.

Potential Side Effects and Considerations:

Like any medication, Mifepristone can have side effects. Common side effects of Mifepristone used for cervical preparation may include:

  • Nausea;
  • Vaginal bleeding;
  • Cramping.

Patients should be informed about these potential side effects and advised on how to manage them. It’s important to report any concerning or persistent side effects to the healthcare provider.

Inducing Labor with Mifepristone When Oxytocin and Prostaglandin Usage is Contraindicated

Inducing labor artificially is sometimes necessary to ensure the health and well-being of both the mother and the unborn child. While oxytocin and prostaglandins are commonly used medications for labor induction, there are situations where their usage is contraindicated due to specific medical conditions or other factors.

In such cases, Mifepristone emerges as a viable alternative for safely and effectively initiating labor. This article delves into the use of Mifepristone for labor induction when oxytocin and prostaglandins cannot be used, its mechanism of action, safety considerations, and implications for maternal and fetal health.

The Role of Mifepristone in Labor Induction

Mifepristone, also known as the abortion pill, is an anti-progesterone medication that is widely used in medical abortion procedures. However, its ability to block progesterone receptors and soften the cervix also makes it a promising option for inducing labor.

When oxytocin and prostaglandins are contraindicated, Mifepristone can be administered to prepare the cervix and promote uterine contractions, leading to the onset of labor.

Situations Where Oxytocin and Prostaglandin Usage is Contraindicated

There are several scenarios in which the use of oxytocin and prostaglandins for labor induction may be contraindicated, including:

  1. Previous Uterine Surgery: Women who have had prior uterine surgeries, such as a cesarean section, may be advised against the use of prostaglandins due to the risk of uterine rupture.
  2. Placental Abnormalities: Certain placental abnormalities or complications may preclude the use of oxytocin or prostaglandins for labor induction to avoid exacerbating the condition.
  3. Fetal Distress: In cases of fetal distress or other fetal complications, alternative methods of labor induction may be necessary to minimize risks to the baby.

Administration and Dosage of Mifepristone for Labor Induction

When Mifepristone is chosen as the method for labor induction, it is typically administered orally or in some cases vaginally. The dosage and timing of Mifepristone may vary depending on the specific medical situation, and it is essential to follow the healthcare provider’s instructions closely. Monitoring maternal and fetal well-being throughout the induction process is crucial to ensure a safe and successful outcome.

Safety Considerations and Monitoring

While Mifepristone is generally considered safe for labor induction, close monitoring of maternal and fetal well-being is essential during the induction process. Healthcare providers will carefully assess the progress of labor, maternal vital signs, and fetal heart rate to ensure a smooth and safe delivery.

Additionally, patients should be informed about the potential side effects of Mifepristone and instructed on when to seek medical attention if necessary.

Treatment of Leiomyoma with Mifepristone

Leiomyomas, or fibroids, are common noncancerous growths that develop in the uterus, affecting many women at some point in their lives. While some fibroids are asymptomatic, others can lead to significant discomfort and complications. One emerging treatment approach for leiomyomas involves the use of Mifepristone, a medication that has shown promise in reducing fibroid size and alleviating symptoms.

Understanding Leiomyoma and its Symptoms:

Leiomyomas are benign tumors that can develop in the muscular wall of the uterus. Common symptoms of leiomyomas include heavy menstrual bleeding, pelvic pain, frequent urination, constipation, and pressure or pain in the lower abdomen. The size and location of fibroids can influence the severity of symptoms and the appropriate treatment approach.

Overview of Mifepristone in the Treatment of Leiomyoma:

Mifepristone, also known as RU-486, is a medication that acts as a progesterone receptor antagonist. Progesterone is a hormone that can stimulate the growth of fibroids. By blocking the action of progesterone, Mifepristone can help reduce fibroid size and alleviate associated symptoms such as heavy bleeding and pelvic pain.

Efficacy of Mifepristone in Treating Leiomyoma:

Research studies have shown promising results regarding the efficacy of Mifepristone in the treatment of leiomyomas. A systematic review published in the Cochrane Database of Systematic Reviews in 2017 found that Mifepristone was effective in reducing fibroid size and improving symptoms in women with leiomyomas. However, further research is needed to establish the long-term effectiveness and safety of this treatment approach.

Potential Side Effects of Mifepristone:

While Mifepristone can be effective in treating leiomyomas, it is important to consider the potential side effects associated with this medication. Common side effects may include nausea, fatigue, changes in appetite, and potential endometrial thickening, which could lead to abnormal bleeding. Patients considering Mifepristone should discuss these risks with their healthcare provider.

Considerations for Patients:

Before opting for Mifepristone treatment for leiomyomas, patients should undergo a comprehensive evaluation and discuss their individual medical history, symptoms, and treatment goals with their healthcare provider. It is essential to weigh the potential benefits of Mifepristone against its risks and consider alternative treatment options, including hormonal medications, minimally invasive procedures, and surgery, depending on the specific circumstances.

Contraindications to use:

  • Pregnancy for more than 77 days;
  • Pathological ectopic fertilization;
  • Unconfirmed pregnancy.

Common contraindications include:

  • Hereditary porphyrin disease;
  • Severe bronchial asthma;
  • Chronic liver or adrenal insufficiency;
  • Individual intolerance to hormonal drugs;
  • Severe anemia.

In the presence of inflammatory diseases, eclampsia, severe gestosis, incorrect positions, or large fetal sizes, Mifepristone as an inducer of labor is contraindicated.

General Side effects:

  • Diarrhea;
  • Abdominal pain;
  • Headache;
  • Severe allergic reaction (anaphylaxis);
  • Anemia;
  • Abnormal heartbeat;
  • Chest pain;
  • Gas (flatulence);
  • Gastrointestinal bleeding;
  • Hearing loss;
  • Heart attack (myocardial infarction);
  • Nausea;
  • Vomiting;
  • Constipation;
  • Rupture of the uterus;
  • Blood clots.

Features of interaction with other drugs

Mifepristone’s potential medication interactions have not been studied in detail. In contrast, the antibiotic Rifampicin, the hormone medication Dexamethasone, and a few anticonvulsants (Carbamazepine and Phenobarbital) are known to lower Mifepristone levels in the blood serum. In contrast, the blood concentration of antifungal medications like Itraconazole and Ketoconazole and the antibiotic Erythromycin increases.

Where can I buy Mifepristone?

We provide an online store where you may get Mifepristone and other abortion drugs. We make every effort to ensure that our customers have a great experience with their Medical Abortion at Home without needing surgery.

What is the price of the Mifepristone tablet in dollars?

Mifepristone is available for a reasonable price on our website, and it will be sent to your door as soon as possible. We also provide expedited delivery, overnight shipping, and additional options to make your purchasing experience as simple as possible.

What is the best place to get the Mifepristone kit?

Using the internet, you may simply and conveniently order a Mifepristone kit from the comfort of your own home. Get a Mifepristone kit from our 24/7 online shop.

Since the Food and Drug Administration authorized them, our products have been safe and effective. Furthermore, with our secure data and transaction system and stealthy packaging, we protect your privacy both online and offline.

When should I consult a doctor if I take Mifepristone for Medical Abortion?

Here are some key situations where you should consult a doctor when undergoing a medical abortion:

1. Excessive Bleeding: Some bleeding is normal during a medical abortion, similar to a heavy period. However, if you experience soaking through more than two pads per hour for two consecutive hours or passing blood clots larger than a lemon, seek medical help immediately.

2. Severe Abdominal Pain: Cramping and abdominal pain are expected during a medical abortion, but if the pain becomes unbearable and is not relieved by over-the-counter pain medications, it could indicate a complication that requires medical attention.

3. Fever: A low-grade fever is common after a medical abortion, but a high fever (above 100.4°F or 38°C) could be a sign of infection and should prompt you to contact a healthcare provider.

4. Foul-smelling Discharge: If you notice a foul odor coming from your vaginal discharge or experience an abnormal amount of discharge, it could be a sign of infection and should be evaluated by a doctor.

5. Incomplete Abortion: In some cases, the medical abortion may not be successful in fully expelling the pregnancy tissue. Signs of an incomplete abortion include persistent bleeding, cramping, and the passage of large clots. If you suspect this is happening, see a healthcare provider for further evaluation.

6. Prolonged Symptoms: While it is normal to experience bleeding and cramping for a few days after a medical abortion, if these symptoms persist for more than two weeks or if you have concerns about your recovery, consulting a doctor is advisable.

7. Emotional Distress: It is common to experience a range of emotions during and after a medical abortion. If you are feeling overwhelmed, anxious, or depressed, seeking mental health support from a counselor or therapist is important for your overall well-being.

Source.

Add a review

Your email address will not be published. Required fields are marked *

There are no reviews yet.